Corporate History

Licensing

In December 2003, the University of Cambridge UK granted ProteinLogic Ltd a worldwide, exclusive license to commercially exploit the intellectual property owned by Cambridge University UK, Addenbrooke's NHS Trust (now Cambridge University Hospitals NHS Foundation Trust), and the Medical Research Council (MRC).

Technology Developers

The technology was developed by Dr César Milstein and Dr Adrian Woolfson at the MRC Laboratory of Molecular Biology in Cambridge UK. They were subsequently joined by Professor Nick Hales from the Department of Clinical Biochemistry at the University of Cambridge UK. The ImmiPrint™ diagnostic technology is partly based on work on monoclonal antibodies, for which Milstein was awarded the Nobel Prize in Medicine and Physiology.

ImmiPrint™ Diagnostic Technology

Unlike existing diagnostic systems, which measure only a single or at most two to three specific proteins, ImmiPrint™ Diagnostic Technology uses high-throughput multiplexing and monoclonal antibodies to measure multiple body fluid proteins in parallel.

Powerful pattern recognition software developed by the team in Cambridge UK, in conjunction with Cambridge University's Physics Department, is then used to analyse large databases of individual proteomic profiles to generate disease-specific biomarker signatures.

Applications

ImmiPrint™ technology provides a way to identify diagnostic biomarker signatures through a single blood or other body fluid test.

The key to the technology is the protein content that ProteinLogic Ltd has identified.

By focusing on a small, discreet, logical and finite set of diagnostic biomarkers, ProteinLogic Ltd has solved the 'content problem', and significantly reduced the dimensions of complexity associated with the proteomic analysis of complex protein solutions.

ImmiPrint™ technology is unique in that it enables the same set of biomarkers to be used for all disease types, each of which has its own characteristic proteomic barcode. ImmiPrint™ technology is a universal search engine for the rapid, efficient and cost-effective discovery of diagnostic biomarker signatures.